Visual-servoing optical microscopy
US8548745B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | May 13, 2011 |
| Grant date | Oct 1, 2013 |
| Priority date | — |
| Expiry date | Jun 4, 2031 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12M41/48
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention provides methods and devices for the knowledge-based discovery and optimization of differences between cell types. In particular, the present invention provides visual servoing optical microscopy, as well as analysis methods. The present invention provides means for the close monitoring of hundreds of individual, living cells over time; quantification of dynamic physiological responses in multiple channels; real-time digital image segmentation and analysis; intelligent, repetitive computer-applied cell stress and cell stimulation; and the ability to return to the same field of cells for long-term studies and observation. The present invention further provides means to optimize culture conditions for specific subpopulations of cells.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.