Systems and methods for use in freezing or thawing biopharmaceutical materials
US8550703B2 · kind B2 · utility
Assignee
Inventor
Key dates
| Filing date | Sep 27, 2010 |
| Grant date | Oct 8, 2013 |
| Priority date | — |
| Expiry date | Aug 28, 2031 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2291/101
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A system for use in freezing or thawing a biopharmaceutical material includes a container means and a support member. The container means has a receiving cavity receiving the biopharmaceutical material therein. The support member is connected to and supported by the container means. A transmitter is configured to propagate an ultrasonic pulse into the biopharmaceutical material and is located in a support member cavity of the support member. An ultrasonic sensor is configured to sense a reflection of the pulse in the biopharmaceutical material and is located in the support member cavity. A controller is coupled to the transmitter and the sensor. The controller is configured to determine a phase change of the biopharmaceutical material based on the propagation of the pulse by the transmitter and the sense of the reflection by the sensor.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.