Bioluminescent detection of cyanohydroxy benzothiazole compounds
US8551721B2 · kind B2 · utility
4Cited by
3References
33Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 9, 2009 |
| Grant date | Oct 8, 2013 |
| Priority date | — |
| Expiry date | Nov 16, 2031 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2326/00
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The invention provides methods that employ derivatives of 2-cyano-6-hydroxy- or 2-cyano-6-amino-benzothiazole, for example, in a bioluminogenic reaction. Also provided are novel compounds that can be used in the methods. The invention further provides methods for detecting or determining the presence of molecules and/or enzymes, the modulator activity of such molecules, and/or the activity of such enzymes. The methods are adaptable to high-throughput format.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.