Peptide analogues, particularly for the treatment of chronic pain
US8551939B2 · kind B2 · utility
0Cited by
3References
12Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Jun 3, 2009 |
| Grant date | Oct 8, 2013 |
| Priority date | — |
| Expiry date | Jun 3, 2029 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The use is claimed of opioid peptides with a novel structure, which in addition to the pharmacophore contain structural elements that interact with neurotensisn receptors. Due to the synergistic interaction with the additional element, an augmented analgesic activity is obtained, capable of being used for an extended period due to decreased drug tolerance induction. These compounds may be of particular use in the treatment of chronic pain as effective analgesics during inflammation caused by rheumatoid, gout, neurodegeneration, post-operative or post-accidental lesions, or oncogenic lesions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.