Methods for generation of antibodies
US8551968B2 · kind B2 · utility
5Cited by
9References
12Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 13, 2008 |
| Grant date | Oct 8, 2013 |
| Priority date | — |
| Expiry date | Apr 27, 2031 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2760/16134
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention generally relates to methods for the production of antibody producing cells and antibodies in protooncogene expressing animals. The invention also relates to methods for the efficient production of antibodies specific for antigens that are normally subject to immunological constraints such as self tolerance. The invention further relates to the production of antibody producing cells and antibodies without the need for the conventional fusing of antibody producing B cells with a myeloma fusion partner.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.