Multifunctional aptamer-nucleic acid nanostructures for tumor-targeted killing
US8552167B2 · kind B2 · utility
7Cited by
1References
24Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 7, 2010 |
| Grant date | Oct 8, 2013 |
| Priority date | — |
| Expiry date | Oct 7, 2030 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2310/3519
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention provides compositions comprising a ligand-nucleic acid nanostructure that promote tumor cell-specific killing and methods of using the compositions. Specially, the invention provides aptamer-nucleic acid nanostructures for treating tumors in a mammal. The methods of making the compositions are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.