Patent · US Active

Process for the covalent coupling of two molecules by means of a diels-alder reaction with inverse electron requirement

US8552183B2 · kind B2 · utility

13Cited by

0References

9Claims

0Family size

Assignee

DEUTSCHES KREBSFORSCHUNGSZENTRUM STIFTUNG DES ÖFFENTLICHEN RECHTS · DE

Inventors

Manfred Wiessler · Bischofswerda, DE
Eduard Muller · Ettenhausen, CH
Peter Lorenz · Jefferson, US
Christian Kliem · Heppenheim, DE
Heinz Fleischhacker · Dossenheim, DE

Key dates

Filing date	Jun 18, 2007
Grant date	Oct 8, 2013
Priority date	—
Expiry date	Sep 23, 2028

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D491/08
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

The present invention relates to a process for linking two molecules by means of a Diels Alder reaction with inverse electron requirement (DARinv), comprising the following steps: reaction of a (a) triazine or tetrazine with one or more electron-attracting substituents on the ring as a diene component, the electron-attracting substituents being selected from:

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.