Patent · US Active

Salt forms of [R-(R*,R*)]-2-(4-fluorophenyl)-beta, delta-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic acid

US8552207B2 · kind B2 · utility

5Cited by
12References
3Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJun 29, 2012
Grant dateOct 8, 2013
Priority date
Expiry dateJun 29, 2032

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D295/037
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Novel salt forms of [R—(R*,R*)]-2-(4-fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic acid characterized by their X-ray powder diffraction pattern and solid-state NMR spectra are described, as well as methods for the preparation and pharmaceutical composition of the same, which are useful as agents for treating hyperlipidemia, hypercholesterolemia, osteoporosis, benign prostatic hyperplasia, and Alzheimer's Disease.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.