Patent · US Active

Methods and systems for in-vitro analysis of biological cells and/or microorganisms

US8552383B2 · kind B2 · utility

0Cited by

5References

8Claims

0Family size

Assignee

TETEC Tissue Engineering Technologies AG · DE

Inventors

Heinz Walter Joseph · Starnberg, DE
Nicolas Lembert · Reutlingen, DE

Key dates

Filing date	Sep 15, 2009
Grant date	Oct 8, 2013
Priority date	—
Expiry date	Sep 15, 2029

Classification

Technology area (CPC G)Physics
CPC primaryG06F2218/12
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

Methods for in-vitro analysis of biological cells and/or microorganisms to determine characteristics such as: degree of differentiation, cell type, donor individuals, culture conditions, purity, lack of natural characteristic, or additional characteristics in comparison to natural characteristics. The methods include the steps of: (a) projecting infrared radiation on a sample; (b) recording spectral characteristics of the sample; (c) deriving a Fourier transform infrared spectrum (FT-IR) from the collected spectral characteristics; (d) generating a derivative transformation of the FT-IR spectrum; (e) comparing said derivative transformation with a derivative of a reference FT-IR spectrum; (f) identifying deviations of said derivative from said reference derivative; and (g) providing an analysis of said characteristics based on the presence of said deviations. In addition, the invention relates to an apparatus for carrying out the disclosed methods.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.