Unifying reconstruction and motion estimation in first pass cardiac perfusion imaging

US8553964B2 · kind B2 · utility

Assignee

• Siemens Aktiengesellschaft · DE

Inventors

• Christophe Chefd'hotel · Jersey City, US
• Mathews Jacob · Iowa City, US
• Sajan Goud Lingala · Hickory Corner, US
• Mariappan S. Nadar · Plainsboro, US
• Li Zhang · Skillman, US

Key dates

• Filing date: Oct 14, 2011
• Grant date: Oct 8, 2013
• Expiry date: Jan 19, 2032

Classification

• Technology area (CPC G): Physics
• CPC primary: G01R33/5611
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

Methods and a system to unify reconstruction and motion estimation steps in first pass cardiac perfusion MRI include a global objective function that meets data consistency, spatial smoothness, motion and contrast dynamics constraints. The global objective decomposed into simpler sub-problems which include low pass filtering of a deformed object, TV shrinkage, analytical Fourier replacement and an l2 minimizing problem. A registration tool based on the local cross-correlation similarity measure and enabled to perform both rigid and flexile deformations, is applied. Registration parameters are tuned by rigid, semi rigid and flexible models at different stages of iterations. A system to perform the methods is also disclosed.