Method and apparatus for microscopy
US8554344B2 · kind B2 · utility
Inventors
Key dates
| Filing date | Mar 13, 2009 |
| Grant date | Oct 8, 2013 |
| Priority date | — |
| Expiry date | Oct 25, 2029 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG05B2219/49368
- WIPO fieldControl
- WIPO sectorInstruments
Abstract
The present invention relates to a compact motorized rotational stage for microscopy applications and control methods for automated sample orientation/rotation. The rotational stage includes a motor, a rotational motion transmission mechanism, and a rotating sample holder for accommodating a holding device such as glass slides/Petri dishes of different sizes. Mouse embryos are used as an example to explain the control methods. A pattern recognition utility was developed for identifying mouse embryo structures. The transformation between the holding device rotational coordinate frame and the translational positioning stage coordinate frame is calibrated during image-based visual servo control. The polar body of an embryo is oriented through purely image-based visual servo control or through coordinate transformation and closed-loop position control.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.