Method for detecting and distinguishing intrahepatic cholangiocarcinoma
US8557602B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Feb 23, 2010 |
| Grant date | Oct 15, 2013 |
| Priority date | — |
| Expiry date | Feb 23, 2030 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/57446
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Disclosed are a method for early, sensitively and reliably detecting and distinguishing intrahepatic cholangiocarcinoma in a malignant tumor occurring primarily in the liver in a simple way, and a kit thereof. In the method, a glycan biomarker consisting of a lectin WFA (Wisteria floribunda Agglutinin)-binding glycoprotein derived from intrahepatic cholangiocarcinoma is used as a cancer marker to detect intrahepatic cholangiocarcinoma by detecting the cancer marker in a test specimen. The method for detecting intrahepatic cholangiocarcinoma can clearly differentiate intrahepatic cholangiocarcinoma from hepatocellular carcinoma and enables early detection and determination with a performance clinically acceptable in terms of applicability, sensitivity and precision.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.