High throughput screens for small-molecule inhibitors of the nuclear receptor-like pathway regulating multidrug resistance in fungi
US8557746B2 · kind B2 · utility
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Key dates
| Filing date | Mar 31, 2010 |
| Grant date | Oct 15, 2013 |
| Priority date | — |
| Expiry date | Dec 16, 2031 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/37
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention relates to the identification of molecular mechanisms associated with multidrug resistance (MDR) in fungal infections. More specifically, fungi harbor a nuclear receptor-like pathway controlling MDR, which represents a novel therapeutic target for the treatment of MDR in pathogenic fungi such as C. glabrata.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.