Compounds and methods for 18F labeled agents

US8557776B2 · kind B2 · utility

Assignee

• Bayer Pharma Aktiengesellschaft · DE

Inventors

• Lutz Lehmann · Berlin, DE
• Ananth Srinivasan · Stanford, US
• Thomas Brumby · Berlin, DE
• Detlef Suelzle · Berlin, DE
• Timo Stellfeld · Berlin, DE
• Keith Graham · Berlin, DE
• Mylene Tania Karramkam · Baie-Mahault, FR
• Simon M. Ametamey · Bellinzona, CH

Key dates

• Filing date: Sep 7, 2007
• Grant date: Oct 15, 2013
• Expiry date: Nov 28, 2028

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K14/57545
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to novel compounds suitable for or already radiolabeled with 18F, methods of making such compounds and use of such compounds for diagnostic imaging. Such labeled compounds are characterized by Formula II, wherein the substituents G, Q, L, Y and U have the meaning as defined in the specification and claims.