Family of PFKFB3 inhibitors with anti-neoplastic activities
US8557823B2 · kind B2 · utility
18Cited by
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3Claims
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Key dates
| Filing date | Nov 30, 2011 |
| Grant date | Oct 15, 2013 |
| Priority date | — |
| Expiry date | Nov 30, 2031 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P35/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A methods and compounds for inhibiting 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (PFKFB3) are described. Also described are methods of inhibiting cell proliferation, treating cancer, and screening compounds to determine their ability to inhibit PFKFB3.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.