Heteroaryl-substituted alkyne compounds and method of use
US8557996B2 · kind B2 · utility
10Cited by
4References
13Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 2, 2010 |
| Grant date | Oct 15, 2013 |
| Priority date | — |
| Expiry date | Apr 17, 2031 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D471/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention comprises a new class of compounds useful for the prophylaxis and treatment of protein kinase mediated diseases, including inflammation, cancer and related conditions. The compounds have a general Formula Iwherein A1, A2, A3, A4, R1 and R2 are defined herein. Accordingly, the invention also comprises pharmaceutical compositions comprising the compounds of the invention, methods for the prophylaxis and treatment of kinase mediated diseases using the compounds and compositions of the invention, and intermediates and processes useful for the preparation of compounds of the invention.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.