Means and method for diagnosing hemolytic anemia

US8563253B2 · kind B2 · utility

Assignee

• Metanomics GmbH · DE

Inventors

• Tilmann B. Walk · Kleinmachnow, DE
• Ralf Looser · Berlin, DE
• Michael Manfred Herold · Berlin, DE
• Jan C. Wiemer · Berlin, DE
• Alexandre Prokoudine · Berlin, DE
• Edgar Leibold · Bischofswerda, DE
• Bennard van Ravenzwaay · Altrip, DE
• Werner Mellert · Haßloch, DE
• Georgia Coelho Palermo Cunha · São Paulo, BR
• Eric Fabian · Ludwigshafen, DE
• Volker Strauss · Bad Dürkheim, DE

Key dates

• Filing date: Jun 4, 2007
• Grant date: Oct 22, 2013
• Expiry date: Nov 1, 2028

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10T436/145555
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

The present invention relates to a method for diagnosing hemolytic anemia or a predisposition thereof. It also relates to a method of determining whether a compound is capable of inducing hemolytic anemia in a subject and to a method of identifying a drug for treating hemolytic anemia. Furthermore, the present invention relates to a data collection comprising characteristic values of metabolites, a data storage medium comprising said data collection, and a system and a device for diagnosing hemolytic anemia. Finally, the present invention pertains to the use of a group of metabolites or means for the determination thereof for the manufacture of a diagnostic device or composition for diagnosing hemolytic anemia in a subject.