Aminotetraline derivatives, pharmaceutical compositions containing them, and their use in therapy

US8563617B2 · kind B2 · utility

Assignees

• Abb Vie Deutschland Gmbh & Co. KG · DE
• Abbott Laboratories · US

Inventors

• Wilhelm Amberg · Ludwigshafen, DE
• Michael Ochse · Wiesbaden, DE
• Udo Lange · Ludwigshafen, DE
• Andreas Kling · Mannheim, DE
• Berthold Behl · Ludwigshafen, DE
• Wilfried Homberger · Ludwigshafen, DE
• Mario Mezler · Ludwigshafen, DE
• Charles W. Hutchins · Libertyville, US

Key dates

• Filing date: Feb 16, 2010
• Grant date: Oct 22, 2013
• Expiry date: Jun 20, 2031

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C2602/10
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The present invention relates to aminotetraline derivatives of the formula (I)or a physiologically tolerated salt thereof.The invention relates to pharmaceutical compositions comprising such aminotetraline derivatives, and the use of such aminotetraline derivatives for therapeutic purposes. The aminotetraline derivatives are GlyT1 inhibitors.