Process for preparing ketones, in particular macrocyclic ketones

US8563781B2 · kind B2 · utility

Assignee

• BASF SE

Inventors

• Michael Schelper · Ludwigshafen, DE
• Christoph Stock · Ellerstadt, DE
• Klaus Ebel · Lampertheim, DE
• Joaquim Henrique Teles · Waldsee, DE
• Ralf Pelzer · Rastenberg, DE

Key dates

• Filing date: Oct 7, 2011
• Grant date: Oct 22, 2013
• Expiry date: Apr 20, 2032

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C2601/18
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Ketones of the formula IIwhere A is optionally alkyl-substituted C2-C12-alkanediyl, R1 and R2 are each, independently of one another, C1-C6-alkyl, or R1 and R2 together form optionally alkyl-substituted C3-C10-alkanediyl, and R3 is hydrogen or C1-C6-alkyl, are prepared by reacting a cyclic olefin of the formula Iwith dinitrogen monoxide to form the ketone of the formula II. The ketone of the formula II can be further hydrogenated to form the saturated ketone of the formula III.Macrocyclic ketones of the formula III, e.g. muscone, are sought after as fragrances.