Cyclin based inhibitors of CDK2 and CDK4
US8566072B2 · kind B2 · utility
8Cited by
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17Claims
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Key dates
| Filing date | Apr 18, 2011 |
| Grant date | Oct 22, 2013 |
| Priority date | — |
| Expiry date | Jun 16, 2031 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG16B20/00
- WIPO fieldComputer technology
- WIPO sectorElectrical engineering
Abstract
Structural and functional analysis of peptide inhibitor binding to the cyclin D1 groove has been investigated and used to design peptides that provide the basis for structure-activity relationships, have improved binding and have potential for development as chemical biology probes, as potential diagnostics and as therapeutics in the treatment of proliferative diseases including cancer and inflammation.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.