Light emitting microorganisms and cells for diagnosis and therapy of tumors
US8568707B2 · kind B2 · utility
24Cited by
97References
18Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 10, 2004 |
| Grant date | Oct 29, 2013 |
| Priority date | — |
| Expiry date | Jun 10, 2024 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2710/24132
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided are diagnostic and pharmaceutical compositions containing a microorganism or a cell containing a DNA molecule encoding a detectable protein or a protein that a detectable signal, such as a luminescent or fluorescent protein. Methods of tumor targeting and tumor imaging using the microorganisms and cells are provided. Also provided are therapeutic methods in which the microorganisms and cells, which can encoded a therapeutic protein, such as a cytotoxic or cytostatic protein, are administered.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.