Patent · US Active

High concentration antibody-containing liquid formulation

US8568720B2 · kind B2 · utility

36Cited by

31References

2Claims

0Family size

Assignees

CHUGAI SEIYAKU KABUSHIKI KAISHA · JP
F. Hoffmann-La Roche AG · CH

Inventors

Toshiyuki MORICHIKA · Osaka, JP
Daisuke Kameoka · Tokyo, JP
Yoshimi IMAEDA · Tokyo, JP
Terutoshi MAEDA · Tokyo, JP
Oliver Boris Stauch · Glückstadt, DE

Key dates

Filing date	Dec 26, 2008
Grant date	Oct 29, 2013
Priority date	—
Expiry date	Nov 5, 2029

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2317/76
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The problem to be solved is to provide an antibody-containing formulation which is stable and suited for subcutaneous administration, wherein dimerization and deamidation is prevented during long-term storage. The present application is directed to a stable antibody-containing liquid formulation characterized by containing arginine and methionine.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.