Patent · US Active

Polypeptide derivatives of parathyroid hormone (PTH)

US8568736B2 · kind B2 · utility

1Cited by
93References
10Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMar 21, 2008
Grant dateOct 29, 2013
Priority date
Expiry dateMay 4, 2030

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61K38/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Novel parathyroid hormone (PTH) polypeptide derivatives are disclosed, as are pharmaceutical compositions containing said polypeptides, and synthetic and recombinant methods for producing said polypeptides. Also disclosed are methods for treating mammalian conditions characterized by decreases in bone mass using therapeutically effective pharmaceutical compositions containing said polypeptides. Also disclosed are methods for screening candidate compounds of the invention for antagonistic or agonistic effects on parathyroid hormone receptor action. Also disclosed are diagnostic and therapeutic methods of said compounds.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.