Patent · US Active

Multiparticulate form of administration, comprising nucleic acid-containing mucoadhesive active ingredients, and method for producing said form of administration

US8568778B2 · kind B2 · utility

4Cited by

1References

26Claims

0Family size

Assignee

Evonik Röhm GmbH · DE

Inventors

Rosario Lizio · Dieburg, DE
Hans-Ulrich Petereit · Darmstadt, DE
Dave Trupti · Zwingenberg, DE
Michael J. Gottschalk · Ober-Ramstadt, DE

Key dates

Filing date	Nov 5, 2005
Grant date	Oct 29, 2013
Priority date	—
Expiry date	Nov 26, 2028

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61K9/1652
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The invention relates to an oral, multiparticulate form of administration, comprising pellets in the size ranging from 50 to 2500 $g(m)m which are substantially constituted of a) an inner matrix layer containing nanoparticles that contain a nucleic acid active ingredient and being embedded in a matrix of a polymer having a mucoadhesive effect, and b) an outer film coating, substantially consisting of an anionic polymer or copolymer that is optionally formulated with pharmaceutically conventional adjuvants, especially emollients.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.