Patent · US Active

Method for modulating responsiveness to steroids

US8569257B2 · kind B2 · utility

2Cited by

22References

36Claims

0Family size

Assignee

Index Pharmaceuticals AB · SE

Inventors

Ann-Kristin Spiik · Tullinge, SE
Robert Lofberg · Djursholm, SE
Lisa Charlotta Bandholtz · Stockholm, SE
Oliver Von Stein · Upplands Väsby, SE
Arezou Zargari · Solna, SE

Key dates

Filing date	Mar 1, 2012
Grant date	Oct 29, 2013
Priority date	—
Expiry date	Mar 1, 2032

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N2310/3233
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

A method for enhancing steroid efficacy in a steroid refractory patient afflicted with an inflammatory condition not responding or responding poorly or inadequately to anti-inflammatory treatment comprises administering an oligonucleotide having the sequence formulain an effective amount to said patient and wherein X is A, T, C or G, Y is A, T, C or G, m=0-7, n=0-7 and wherein at least one CG dinucleotide is unmethylated.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.