Intermediate and process for preparing entecavir using same
US8569490B2 · kind B2 · utility
0Cited by
3References
10Claims
0Family size
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Key dates
| Filing date | Dec 24, 2009 |
| Grant date | Oct 29, 2013 |
| Priority date | — |
| Expiry date | Aug 12, 2030 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P31/12
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention relates to a novel, high-yield and low-cost method for preparing entecavir, [1-S-(1α,3α,4β)]-2-amino-1,9-dihydro-9-[4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one, an antiviral agent, and novel intermediates used therein.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.