System for screening agonists/antagonists of cellular signaling pathways
US8574837B2 · kind B2 · utility
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1References
15Claims
0Family size
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Key dates
| Filing date | Dec 29, 2009 |
| Grant date | Nov 5, 2013 |
| Priority date | — |
| Expiry date | Jun 4, 2030 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/705
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention identifies a method for investigating the response of a cell membrane-associated protein in a living cell to a drug by labeling the protein with a visual marker, and also selectively labeling the membrane portion of the protein with another visual marker, such that upon exposure of the cell to a stimulus, the translocation of the cell membrane-associated protein may be observed directly.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.