Saccharomyces cerevisiae yeast strain with functional expression of a GLUT transporter gene

US8574909B2 · kind B2 · utility

Assignee

• Sanofi-Aventis Deutschland GMBH · DE

Inventors

• Guenter Mueller · Pocking, DE
• Klaus-Peter Koller · Bad Soden, DE
• Eckhard Boles · Dreieich, DE
• Roman Niedbal · Ratingen, DE
• Silke Dlugai · Düsseldorf, DE

Key dates

• Filing date: Apr 7, 2006
• Grant date: Nov 5, 2013
• Expiry date: Jan 16, 2029

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12R2001/865
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention relates to a strain of the yeast Saccharomyces cerevisiae which, owing to deletion of the genomic sequences, no longer synthesizes hexose transporters and, as a consequence, can no longer grow on substrates with hexoses as the only carbon source, and whose ability of growing on a substrate with a hexose as the only carbon source is restored when it expresses a GLUT4 gene.