Methods for mobile zinc measurement

US8574914B2 · kind B2 · utility

Assignees

• The General Hospital Corporation · US
• Massachusetts Institute of Technology · US

Inventors

• Stephen J. Lippard · Cambridge, US
• Xiao-An Zhang · Sunnyvale, US
• Zdravka Medarova · Methuen, US
• Anna Moore · Stoneham, US

Key dates

• Filing date: Aug 12, 2010
• Grant date: Nov 5, 2013
• Expiry date: Aug 12, 2030

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N33/582
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

This invention relates to a method for using a zinc sensor compound to detect a disease associated with the disruption of zinc homeostasis, such as prostate cancer. The zinc sensor compound comprises an optical reporter having two or more recognition units where each of the recognition units is capable of associating with at least one zinc ion.