Thyroglobulin quantitation by mass spectrometry
US8574915B2 · kind B2 · utility
50Cited by
5References
20Claims
0Family size
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Key dates
| Filing date | Apr 9, 2013 |
| Grant date | Nov 5, 2013 |
| Priority date | — |
| Expiry date | Apr 9, 2033 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T436/24
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Provided are methods for determining the amount of thyroglobulin in a sample using various purification steps followed by mass spectrometry. The methods generally involve purifying thyroglobulin in a test sample, digesting thyroglobulin to form peptide T129, purifying peptide T129, ionizing peptide T129, detecting the amount of peptide T129 ion generated, and relating the amount of peptide T129 ion to the amount of thyroglobulin originally present in the sample.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.