BIR domain binding compounds
US8575113B2 · kind B2 · utility
1Cited by
14References
25Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 28, 2010 |
| Grant date | Nov 5, 2013 |
| Priority date | — |
| Expiry date | Aug 27, 2031 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K5/06069
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention is directed towards an isomer, an enantiomer, a diastereoisomer, or a tautomer of a pyrrolidine compound represented by Formula I:in which the substituents R1, R1a, R2, R2a, R3, A and Q are defined herein; or a prodrug, or a salt thereof, and which bind to IAP BIR domains. In particular, the compounds are useful in treating proliferative disorders such as cancer.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.