2′-chloroacetylenyl substituted nucleoside derivatives
US8575119B2 · kind B2 · utility
62Cited by
5References
22Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 21, 2012 |
| Grant date | Nov 5, 2013 |
| Priority date | — |
| Expiry date | Sep 21, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07H19/213
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to 2′-chloroacetylenyl-substituted nucleoside derivatives of the general formula (I):As well as pharmaceutical compositions comprising such compounds and methods to treat or prevent an HIV infection, HBV infection, HCV infection or abnormal cellular proliferation, comprising administering said compounds or compositions. In addition, the present invention includes processes for the preparation of such compounds, and the related β-D and β-L-nucleoside derivatives.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.