Patent · US Active

Benzofurane, benzothiophene, benzothiazol derivatives as FXR modulators

US8575161B2 · kind B2 · utility

1Cited by

7References

28Claims

0Family size

Assignee

Merck Patent GmbH · DE

Inventors

Didier Roche · Écully, FR
Gisèle Mautino · Château-Thierry, FR
Ingo Kober · Groß-Gerau, DE
Francis Contard · Val-de-Reuil, FR
Serge Christmann-Franck · Geneva, CH
Saumitra Sengupta · Basel, CH
Ramesh Kumar Sistla · Bengaluru, IN
Gummadi Venkateshwar Rao · Bengaluru, IN

Key dates

Filing date	Mar 30, 2009
Grant date	Nov 5, 2013
Priority date	—
Expiry date	Jan 12, 2030

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D405/12
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention relates to compounds of formula (I) wherein the substituents are as defined in the claims, including pharmaceutical compositions thereof and for their use in the treatment and/or prevention and/or amelioration of one or more symptoms of disease or disorders related to the activity of FXR. The invention is also directed to intermediates and to a method of preparation of compounds of formula (I).

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.