Flurbiprofen analogs and methods of use in treating cancer
US8575170B2 · kind B2 · utility
1Cited by
3References
17Claims
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Key dates
| Filing date | Feb 25, 2011 |
| Grant date | Nov 5, 2013 |
| Priority date | — |
| Expiry date | Mar 17, 2031 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P35/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Flurbiprofen analog compounds having an amino acid derivatized at the flurbiprofen alkanoic acid carboxyl group and terminating at an ester or amide group are effective in inhibiting cancer cells in vitro and inhibiting the growth of cancers in viva. The compounds and pharmaceutical compositions containing them are particularly useful for the treatment of lung, pancreatic and head and neck cancers.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.