Isothiazolo-pyrimidinedione derivatives as TRPA1 modulators
US8575178B2 · kind B2 · utility
4Cited by
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15Claims
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Key dates
| Filing date | Mar 22, 2010 |
| Grant date | Nov 5, 2013 |
| Priority date | — |
| Expiry date | Apr 15, 2030 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention is related to novel isothiazolo[3,4-d]pyrimidinedione and isothiazolo[5,4-d]pyrimidinedione derivatives as TRPA (Transient Receptor Potential subfamily A) modulators. In particular, compounds described herein are useful for treating or preventing diseases, conditions and/or disorders modulated by TRPA1 (Transient Receptor Potential subfamily A, member 1). Also provided herein are processes for preparing compounds described herein, intermediates used in their synthesis, pharmaceutical compositions thereof, and methods for treating or preventing diseases, conditions and/or disorders modulated by TRPA1.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.