N-substituted tetrahydroisoquinoline/isoindoline hydroxamic acid compounds

US8575193B2 · kind B2 · utility

Assignee

• 4SC AG · DE

Inventors

• Thomas Maier · Stockach, DE
• Thomas Beckers · Konstanz, DE
• Christian Hesslinger · Zoznegg, DE

Key dates

• Filing date: Mar 12, 2009
• Grant date: Nov 5, 2013
• Expiry date: Mar 18, 2029

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D405/06
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Compounds of a certain formula (I) wherein R1, R2, R3, X, Y, r, s, t, u and v have the meanings as defined in the specification, and the salts, solvates and hydrates thereof are novel effective HDAC 6 inhibitors.