Population scale HLA-typing and uses thereof
US8575325B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | May 21, 2012 |
| Grant date | Nov 5, 2013 |
| Priority date | — |
| Expiry date | May 21, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/156
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention provides a portable system for real-time population-scale HLA genotyping and/or allelotyping in a field environment and methods of such population-scale HLA genotyping. The individual components of the system are portable to and operable within a field environment thereby providing high throughput with real-time geno- or allelotyping. Also provided are HLA gene-specific primers and HLA allele-specific or single nucleotide polymorphism-specific hybridization probes. In addition the present invention provides a microarray comprising the hybridization probes. Further provided is a kit comprising the HLA gene-specific primers and the microarray.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.