Immune stimulatory infant nutrition

US8580316B2 · kind B2 · utility

Assignee

• N.V. Nutricia · NL

Inventors

• Günther Boehm · Echzell, DE
• Christopher Beermann · Eisenberg, DE
• Bernd Stahl · Friedrichsdorf, DE
• Laura M'Rabet · Amersfoort, NL
• Johan Garssen · Nieuwegein, NL

Key dates

• Filing date: Jan 27, 2012
• Grant date: Nov 12, 2013
• Expiry date: Jan 27, 2032

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A23V2002/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A nutritional or pharmaceutical composition comprising fat, protein, carbohydrate, whey and casein is provided. The composition has a weight ratio of casein to whey between 1:1 to 1:2.4 and comprises: a) at least 3 grams arginine per 100 grams protein; b) at least 10 wt. % linoleic acid based on total fatty acids; c) at least 1 wt. % alpha linolenic acid based on total fatty acids; d) at least one long chain-polyunsaturated fatty acid in an amount exceeding 0.1 wt. % based on total fatty acids selected from docosahexaenoic acid, arachidonic acid and eicosapentaenoic acid; e) 5 to 25 wt. % of at least one polyunsaturated fatty acid based on total fatty acids; and 2 to 12 grams indigestible oligosaccharides having a degree of polymerisation of 2 to 100 per 100 gram dry weight of the composition. Methods of treatment by administering the composition are also provided.