Methods for identifying compounds which modulate T2R bitter taste receptors

US8580527B2 · kind B2 · utility

Assignee

• The Regents of the University of California · US

Inventors

• Charles S. Zuker · San Diego, US
• Jon Elliot Adler · San Diego, US
• Mark Hoon · Kensington, US
• Nick Ryba · Bethesda, US
• Ken Mueller · San Diego, US

Key dates

• Filing date: Oct 11, 2011
• Grant date: Nov 12, 2013
• Expiry date: Oct 11, 2031

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K14/705
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

The invention provides isolated nucleic acid and amino acid sequences of taste cell specific G-protein coupled receptors, antibodies to such receptors, methods of detecting such nucleic acids and receptors, and methods of screening for modulators of taste cell specific G-protein coupled receptors.