Patent · US Active

Diagnosis of collagen IX destruction

US8580529B2 · kind B2 · utility

1Cited by

2References

2Claims

0Family size

Assignee

ANAMAR AB · SE

Inventors

Mikael Danfelter · Lund, SE
Patrik Önnerfjord · Malmö, SE
Dick Heinegard · Lund, SE

Key dates

Filing date	Dec 22, 2010
Grant date	Nov 12, 2013
Priority date	—
Expiry date	Feb 6, 2031

Classification

Technology area (CPC G)Physics
CPC primaryG01N2800/10
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

A method for detecting or monitoring the presence of protein fragments, cleaved at novel cleaving sites near the N-terminal part of the collagen IX alpha 1 chain, close to the C-terminal part of the NC4 domain, and at the COL3 domain close to the NC3 domain. Neoepitope antibodies against the neoepitopes were created by the cleavages and an epitope in the cleaved N-terminal part of the NC4 domain unique to collagen IX. A diagnostic kit and antibodies useful in carrying out such methods are also presented.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.