[1,2,4]triazolo [1,5-c]pyrimidine derivatives as Hsp90 modulators
US8580783B2 · kind B2 · utility
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11Claims
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Key dates
| Filing date | Sep 3, 2010 |
| Grant date | Nov 12, 2013 |
| Priority date | — |
| Expiry date | Sep 3, 2030 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to [1,2,4]triazolo[1,5-c]pyrimidine derivatives of formula (I) which inhibit the activity of Heat Shock Protein Hsp90. The compounds of the invention are therefore useful in treating proliferative diseases such as cancer and neurodegenerative diseases. The present invention also provides processes for preparing these compounds, methods of treating diseases and the pharmaceutical compositions comprising these compounds.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.