Heteroaryl amide analogues as P2X7 antagonists
US8580812B2 · kind B2 · utility
8Cited by
12References
26Claims
0Family size
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Key dates
| Filing date | Apr 9, 2008 |
| Grant date | Nov 12, 2013 |
| Priority date | — |
| Expiry date | Jun 25, 2029 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D519/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Heteroaryl amide analogues are provided, of Formula (I), wherein variables are as described herein. Such compounds are ligands that may be used to modulate specific receptor activity in vivo or in vitro, and are particularly useful in the treatment of conditions associated with pathological receptor activation in humans, domesticated companion animals and livestock animals. Pharmaceutical compositions and methods for using such compounds to treat such disorders are provided, as are methods for using such ligands for receptor localization studies.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.