Patent · US Active

Method for the manufacturing of naltrexone

US8580963B2 · kind B2 · utility

0Cited by

1References

13Claims

0Family size

Assignee

H. LUNDBECK A/S · DK

Inventors

Carla De Faveri · Isola di Terranegra, IT
Florian Huber · Grassau, DE
Mariano Stivanello · Schio, IT

Key dates

Filing date	Nov 2, 2011
Grant date	Nov 12, 2013
Priority date	—
Expiry date	Jul 24, 2032

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D489/08
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

The present invention relates to an improved process for producing naltrexone[17-(cyclopropylmethyl)-4,5α-epoxy-3,14-dihydroxy-morphinan-6-one] from noroxymorphone[4,5-α-epoxy-3,14-dihydroxy-morphinan-6-one] by alkylation with a cyclopropylmethyl halide.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.