Lysine-based prodrugs of aspartyl protease inhibitors and processes for their preparation
US8580995B2 · kind B2 · utility
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56Claims
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Key dates
| Filing date | Jun 19, 2008 |
| Grant date | Nov 12, 2013 |
| Priority date | — |
| Expiry date | Feb 10, 2030 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F9/091
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention provides processes for synthesizing lysine based compounds of the formula;wherein R1 may be, for example, (HO)2P(O)—, (NaO)2P(O)—, wherein X may be, for example, NH2, Y may be H, F, Cl, or Br, and wherein n, X′, Y′, R2, R3, R4, R5 and R6 are as defined herein.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.