Apparatuses for noninvasive determination of in vivo alcohol concentration using raman spectroscopy
US8581697B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Apr 23, 2008 |
| Grant date | Nov 12, 2013 |
| Priority date | — |
| Expiry date | Aug 20, 2032 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61B5/1455
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
Methods and apparatuses for the determination of an attribute of the tissue of an individual use non-invasive Raman spectroscopy. For example, the alcohol concentration in the blood or tissue of an individual can be determined non-invasively. A portion of the tissue is illuminated with light, the light propagates into the tissue where it is Raman scattered within the tissue. The Raman scattered light is then detected and can be combined with a model relating Raman spectra to alcohol concentration in order to determine the alcohol concentration in the blood or tissue of the individual. Correction techniques can be used to reduce determination errors due to detection of light other than that from Raman scattering from the alcohol in the tissue. Other biologic information can be used in combination with the Raman spectral properties to aid in the determination of alcohol concentration, for example age of the individual, height of the individual, weight of the individual, medical history of the individual and his/her family, ethnicity, skin melanin content, or a combination thereof. The method and apparatus can be highly optimized to provide reproducible and, preferably, uniform radian…
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.