Light emitting microorganisms and cells for diagnosis and therapy of tumors
US8586022B2 · kind B2 · utility
27Cited by
95References
13Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 31, 2007 |
| Grant date | Nov 19, 2013 |
| Priority date | — |
| Expiry date | Oct 4, 2028 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2710/24132
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided are diagnostic and pharmaceutical compositions containing a microorganism or a cell containing a DNA molecule encoding a detectable protein or a protein that a detectable signal, such as a luminescent or fluorescent protein. Methods of tumor targeting and tumor imaging using the microorganisms and cells are provided. Also provided are therapeutic methods in which the microorganisms and cells, which can encoded a therapeutic protein, such as a cytotoxic or cytostatic protein, are administered.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.