Method of producing erythrocytes without feeder cells
US8586360B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jul 1, 2010 |
| Grant date | Nov 19, 2013 |
| Priority date | — |
| Expiry date | Jul 1, 2030 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2506/03
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Provided herein are methods of producing erythrocytes from hematopoietic cells, particularly hematopoietic cells from placental perfusate in combination with hematopoietic cells from umbilical cord blood, wherein the method results in accelerated expansion and differentiation of the hematopoietic cells to more efficiently produce administrable erythrocytes. Further provided herein is a bioreactor in which hematopoietic cell expansion and differentiation takes place.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.