Patent · US Active

18-membered macrocycles and analogs thereof

US8586551B2 · kind B2 · utility

1Cited by
6References
6Claims
0Family size

Assignee

Inventors

Key dates

Filing dateAug 31, 2009
Grant dateNov 19, 2013
Priority date
Expiry dateFeb 11, 2031

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07H17/08
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention relates generally to the 18-membered macrocyclic antimicrobial agents called Tiacumicins, specifically, OPT-80 (which is composed almost entirely of the R-Tiacumicin B), pharmaceutical compositions comprising OPT-80, and methods using OPT-80. In particular, this compound is a potent drug for the treatment of bacterial infections, specifically C. difficile infections.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.