Unsaturated heterocyclic derivatives

US8586566B2 · kind B2 · utility

Assignee

• Ariad Pharmaceuticals, Inc. · US

Inventors

• Yihan Wang · 安丰镇, CN
• Wei-Sheng Huang · Cambridge, US
• Rajeswari Sundaramoorthi · Watertown, US
• Xiaotian Zhu · Newton, US
• R. Mathew Thomas · Sharon, US
• William C. Shakespeare · Framingham, US
• David C. Dalgarno · Brookline, US
• Tomi K. Sawyer · Southborough, US

Key dates

• Filing date: Dec 5, 2011
• Grant date: Nov 19, 2013
• Expiry date: Dec 5, 2031

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P43/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

This invention relates to specific compounds and their pharmaceutically acceptable salts of the general formula:wherein Q is —CR═CR′— and Ring A is an aryl, heteroaryl or heterocyclic ring or ring system. This invention also relates to pharmaceutical compositions comprising such specific compounds or their pharmaceutically acceptable salts and a pharmaceutically acceptable carrier or adjuvant.