N-(Aminoheteroaryl)-1H-indole-2-carboxamide derivatives, and preparation and therapeutic application thereof

US8586573B2 · kind B2 · utility

Assignee

• Sanofi · FR

Inventors

• Laurent Dubois · Le Plessis-Robinson, FR
• Yannick Evanno · Rambouillet, FR
• Andre Malanda · Paris, FR
• David Machnik · Antony, FR
• Catherine Gille · Antony, FR

Key dates

• Filing date: Jul 19, 2010
• Grant date: Nov 19, 2013
• Expiry date: Jun 4, 2031

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D403/12
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention concerns compounds of general formula (I):Wherein n, X1, X2, X3, X4, Y, Z, Z1, Z2, Z3 and Z4 are as defined herein. The invention also concerns a process for the preparation of compounds of formula (I) and their therapeutic use.